The new hardware integrates the StepWave XR Ion Guide, which the company claims provides six times the robustness of its predecessor, the Xevo TQ Absolute. By minimizing the impact of challenging matrix components like salts and phospholipids, the system aims to stabilize ion ratios and extend operational uptime for high-volume diagnostic centers.
Waters Unveils High-Sensitivity Xevo TQ Absolute XR IVD System
Targeting high-stakes clinical fields like women's health and toxicology, Waters Corporation has launched the Xevo TQ Absolute XR IVD Mass Spectrometer. Unveiled at the 2026 ADLM Annual Meeting, the system promises a fivefold increase in sensitivity and enhanced robustness for laboratories managing complex biological samples.

Clinical applications for the device include low-level estradiol testing for hormonal cancer assessment and forensic hair toxicology. James Nutt, head of laboratory operations at Cansford Laboratories, noted that the increased signal stability allows for more reliable quantification when working near critical decision thresholds. The Xevo TQ Absolute XR is now available as part of the broader MassTrak LC-MS/MS IVD portfolio, paired with the ACQUITY UPLC I-Class PLUS System to streamline sample characterization.




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